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NMDAR antagonist 1

CAS No. 2220162-06-9

NMDAR antagonist 1( —— )

Catalog No. M20173 CAS No. 2220162-06-9

NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	88	In Stock
5MG	156	In Stock
10MG	245	In Stock
25MG	471	In Stock
50MG	671	In Stock
100MG	888	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

NMDAR antagonist 1
Note

Research use only, not for human use.
Brief Description

NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR.
Description

NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR.
In Vitro

NMDAR antagonist 1 (Compound 5q) exhibits excellent neuroprotective activity. NMDAR antagonist 1 can attenuate Ca2+ influx induced by NMDA.NMDAR antagonist 1 can suppress the NR2B up-regulation and increase p-ERK1/2 expression.NMDAR antagonist 1 inhibits SH-SY5Y cells with cell viabilities of 75.8%, 80.0%, 84.4%, and 78.6% at 0.1 μM 1 μM 10 μM 100 μM, respectively.
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

2220162-06-9
Formula Weight

414.3
Molecular Formula

C20H20BrN3O2
Purity

>98% (HPLC)
Solubility

——
SMILES

Cc1ccc2N=C3CCC(N3Cc2c1)C(=O)NCCc1ccc(O)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

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