NMDAR antagonist 1

CAS No. 2220162-06-9

NMDAR antagonist 1( —— )

Catalog No. M20173 CAS No. 2220162-06-9

NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NMDAR antagonist 1
  • Note
    Research use only, not for human use.
  • Brief Description
    NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR.
  • Description
    NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR.
  • In Vitro
    NMDAR antagonist 1 (Compound 5q) exhibits excellent neuroprotective activity. NMDAR antagonist 1 can attenuate Ca2+ influx induced by NMDA.NMDAR antagonist 1 can suppress the NR2B up-regulation and increase p-ERK1/2 expression.NMDAR antagonist 1 inhibits SH-SY5Y cells with cell viabilities of 75.8%, 80.0%, 84.4%, and 78.6% at 0.1 μM 1 μM 10 μM 100 μM, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2220162-06-9
  • Formula Weight
    414.3
  • Molecular Formula
    C20H20BrN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1ccc2N=C3CCC(N3Cc2c1)C(=O)NCCc1ccc(O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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